Our Working Hypothesis
We study each cell as a being in a world. A bacterium has surroundings that matter to it, needs it has to meet and a life it has to keep going, so we start from the whole cell and ask what problem it's solving. That's why we use methods that keep wholes intact, like a pattern language, which describes a cell by the problems it keeps running into and the ways it answers them. We don't know yet whether these are the right tools for understanding cells as creatures. We expect to replace some of them.
Concepts
The ideas, in the order they build on each other. A map that runs from the first question all the way to designing new experiments.
Patterns
One living thing, from molecule to society, looked at scale by scale, each time with a figure drawn at true size.
If you read one page, read this one
DraftAdaptation: how a cell learns to ignore a steady signalA swimming cell resets its own receptors so it can keep noticing change. Two figures, and real single-cell data.
Eight strands, from the first question all the way to design
- A Orientation
- B Life at cell scale
- C Sensing and action
- D Memory and learning
- E Collectives
- F Cognition debates
- G Whole-cell program
- H Design
This site is a draft, and will remain so for a while. Every idea and pattern is open for review. The Manifesto is the only piece that's been published in a final version.